Cordyceps has been shown to reduce fatigue and depression through several mechanisms, including: Improving energy production: Cordyceps has been shown to improve energy production in cells, which could help reduce feelings of fatigue. Enhancing physical performance: Cordyceps has been shown to enhance physical performance, which could help reduce feelings of fatigue and improve overall energy levels. Regulating cortisol levels: Cordyceps has been shown to regulate cortisol levels, which is a stress hormone. High cortisol levels can contribute to feelings of fatigue and depression, so regulating cortisol levels could help reduce fatigue and depression. Improving immune function: Cordyceps has been shown to improve immune function, which could help reduce feelings of fatigue and depression. Modulating cytokine production: Cordyceps has been shown to modulate the production of cytokines, which are proteins involved in the immune response. By regulating cytokine production, Cordyceps m