Maitake with polysaccharides as principle constituents has been reported to strongly interact with the immune system.
The mushroom Grifola frondosa contains starch, natural oligofructoses, fructo-oligosacharides (FOS), lactulose, galactomannan, and indigestible polydextrose, indigestible dextrin, and β-glucan.
Grifola frondosa is a species of maitake and its d-fraction is rich in proteoglucan, which has long been exclusively attributed to their immune-stimulatory capacity.
In particular, it decreases cell viability, increases cell adhesion, and reduces the migration and invasion of mammary tumor cells, generating a less aggressive cell behavior in a murine model of breast cancer.
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