Maitake mushroom | Role of Maitake mushrooms in Cancer treatment | Maitake And Cancer

Maitake mushroom | Role of Maitake mushrooms in Cancer treatment | Maitake And Cancer

Maitake mushroom (Grifola frondosa (Dicks) Gray):

  • Maitake (Japanese for “dancing mushroom”) is an edible mushroom that grows in clusters at the foot of oak trees. Maitake (Grifola frondosa) contains grifolan, a beta glucan polysaccharide. 
  • This activates macrophages which search and engulf foreign invaders in the body. Another ingredient, termed d-fraction, stimulates the immune system at the cellular rather than blood stream level. 
  • D-fraction can be used on its own, but seems capable of enhancing the effect of cancer drugs whilst reducing side-effects such as nausea and hair loss. 
  • For medicinal purposes, maitake is used as a dried powder, hot water extracts, or isolated fractions and compounds. β- glucan is the active polysachharide extracted or isolated from fruiting bodies. 
  • This is used in traditional Chinese and Japanese medicine to enhance the immune system (Nanba et al., 1987). Studies have shown that it can enhance both the innate immune response to fight infections as well as adaptive immune response conferring long-term immune enhancement.
  • Maitake also protects cells with its antioxidant properties and decreases the inflammatory factor COX2 enzyme so common in cancer physiology. Studies have also shown that Maitake has potential anti-metastatic properties inhibiting the proliferation and spread of cancer.
Role Of Maitake Mushroom In Cancer Treatment
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