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Shiitake Mushroom | Role Of shiitake Mushroom In Cancer Treatment | Shiitake Mushroom And Cancer

Shiitake Mushroom | Role Of shiitake Mushroom In Cancer Treatment | Shiitake Mushroom And Cancer

Shiitake mushroom (Lentinus edodes (Berk) Sing):

  • Lentinula edodes is an antiproliferative mushroom widely known as Shitake mushroom an edible fungus native to Asia, and cultivated for food in many countries. 
  • The fresh and dried forms of the mushroom are commonly used in East Asian cooking. 
  • Extracts from the mushroom, and sometimes the whole dried mushroom, are used in herbal remedies. 
  • Shiitake mushroom is used for boosting the immune system, lowering blood cholesterol levels, treating prostate cancer, and as an anti-aging. 
  • One shiitake extract called lentinan is a beta glucan. This is a type of complex sugar compound. Beta glucan is believed to stimulate the immune system and trigger certain cells and proteins in the body to attack cancer cells. 
  • In laboratory studies, it seems to slow the growth of some cancer cells. Lentinan, a compound found in Shitake, is used as an intravenous anti-cancer drug with antitumor properties. 
  • Both α and β-glucans derived from shiitake are used as adjuvants in various clinical studies. 
  • Clinical studies have associated lentinan with a higher survival rate, higher quality of life and lower recurrence of cancer. 
  • From a clinical standpoint, AHCC has generally been administered as an adjuvant in combination with surgery and chemotherapy or radiation (Gu and Belury, 2005).
Role Of Shiitake Mushroom In Cancer Treatment
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